In 2015, I gained the privilege of sitting down with Harvard Researcher Michael Hamblin, who is the most published and cited researcher in the world in the field of Photobiomodulation. He has investigated the science behind Photobiomodulation over three decades, including its potential clinical application in management of brain related injuries. He agreed that including my eldest son and nephew (who was studying dentistry at Boston University) was a good strategy, given the amount of work required to advance the technology for wide adoption and clinical application. Dr. Hamblin shared one-of his seminal Papers that describes the game-changing anti-inflammatory mechanism of PBM, which is referenced in the article about its role in Pain Management.
Low back pain (LBP) affects millions worldwide, often leading to chronic
discomfort and disability. Traditional treatments range from medications to invasive
surgeries, each with potential risks and side effects. Photobiomodulation (PBM), also
known as low-level laser therapy (LLLT), has emerged as a non-invasive alternative for
managing LBP.
Understanding Photobiomodulation aka Laser or Light Therapy
PBM involves the application of red and near-infrared light to body tissues, aiming to
stimulate cellular processes that promote healing and reduce inflammation. The primary
target is cytochrome c oxidase in mitochondria, leading to increased ATP production,
modulation of reactive oxygen species, and enhanced nitric oxide release. These effects
collectively contribute to pain relief and tissue repair.
PBM in Low Back Pain Management
Several studies have explored PBM’s efficacy in treating LBP:
Anti-Inflammatory Effects: PBM has been shown to modulate inflammatory mediators, reducing levels of pro-inflammatory cytokines like TNF-a and IL-6. This modulation can alleviate pain and improve function in musculoskeletal disorders, including LBP.
Clinical Efficacy: Research indicates that PBM can effectively reduce pain and disability in chronic non-specific low back pain. A meta-analysis of randomized controlled trials found that PBM provided significant pain relief compared to placebo treatments.
Safety Profile: PBM is generally considered safe, with minimal reported side effects. Its non-invasive nature makes it an attractive option for patients seeking alternatives to pharmacological interventions.
Integrating PBM into Pain Management Strategies
Given the global concerns over opioid use for chronic pain, PBM offers a promising adjunct or alternative therapy. Its ability to reduce inflammation and promote tissue healing addresses the underlying causes of pain rather than merely masking symptoms. Healthcare providers who consider PBM as part of a comprehensive pain management plan, observe potentially reduction in reliance on opioids and improving patient outcomes.
Future looking
Photobiomodulation already presents a viable, non-invasive treatment option for individuals suffering from low back pain. Its mechanisms targeting inflammation and cellular repair offer a holistic approach to pain management. As research continues to support its efficacy and safety, PBM is estimated to become an integral component of standard care for chronic pain conditions, worldwide.
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